Vapourtec have collaborated with Innovate UK award winning catalyst manufacturer Stoli Catalysts Ltd to demonstrate a new range of catalyst-coated tube reactors for continuous flow selective hydrogenation.
Projects & Collaborations
Regioselective heterogeneous catalytic hydrogenation forms the basis of a vast array of important industrial and laboratory based applications.
It is widely recognised that variations in virtually every possible parameter can affect the regioselectivity of the reaction, including the catalyst, solvent, pressure, and temperature.
With this application note, our Stoli catalyst-coated reactor is paired with the Vapourtec R-Series system for the regioselective reduction of cinnamaldehyde. A surprisingly complex hydrogenation, this model reaction can produce the desired cinnamyl alcohol, or phenylpropanal, by mono-hyfrogenation, or the double hydrogenation product phenylpropanol. This application readily illustrates the remarkable ease with which these reactions can be carried out and controlled using the Vapourtec R-series.
In conjunction with our commitments to achieve environmental sustainability, a Life Cycle Analysis in accordance with ISO 14040 was conducted to compare Stoli Technology with existing methods for semihydrogenation.
Semihydrogenation is an important industrial chemical reaction as it is widely used by the industry for processes such as vitamin intermediate synthesis and hydrorefining. Conventional methods involve the use of toxic lead based Lindlar catalyst in a batch reactor which is not only an inefficient way of chemical manufacturing, but has severe environmental impacts.
To improve upon current standards, Stoli catalysts developed a novel technology which involves solvent free semihydrogenation of an alkyne to alkene in a capillary reactor by coating it with a Titania supported palladium-bismuth catalyst. This allows for several advantages which are :
-No solvent involved
-Significantly less emissions to the environment
(Details of this technology can be accessed by clicking HERE)
The results of the LCA reveal that continuous processing is far superior than batch processing in 3 endpoint categories that are scrutinized which are damage to human health, damage to ecosystem diversity and damage to resource availability.